The laboratory tests were compared between the two groups. The patients were divided into two groups: perforated appendicitis (18 cases) and non-perforated appendicitis (43 cases). Before surgery, venous samples were obtained and serum amylase, lipase, alanine aminotransferase (ALT), aspartate aminotransferase (AST), and alkaline phosphatase were assayed. The diagnosis of appendicitis was confirmed with histopathologic examination. In this cross-sectional study, 61 children (aged 3 to 15 years) who underwent appendectomy surgery due to acute appendicitis at two university hospitals in Kermanshah, Iran, from 2015 to 2016 were included. The objective of the current study was to determine the diagnostic accuracy of raised serum amylase level in prediction of perforated appendicitis in children with acute appendicitis. Recent studies indicate increased serum amylase in children with acute appendicitis.
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